The A27 was partially blocked after reports of an accident involving a coach and two cars.
The A27 at Crockhurst Hill, near Warren Road in Worthing, was partially blocked and there is slow traffic in both directions near Offington Corner.
Sussex Police said it received a call at 5.05pm saying a coach was on fire in Crockurst Hill on the A24, but that the vehicle was not there when officers arrived at the scene.
The road is no longer blocked.
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